Nanotechnology presents An array of opportunities to contribute to biology. Right here I will current examples the place nanofabrication – the opportunity to make confined constructions with Proportions at will – is applied to look at the biophysics of one molecules and cells. I will present some examples from our lab:

Our group scientific tests bacterial cell division which is aiming to represent a ‘bottom up biology’ in artificial cells which can autonomously divide. Our principal desire lies in cell division, chromatin construction, and spatial Command.

Being a individual, I have the biblical assignment to investigate and use anything in generation for the benefit of my neighbour. I usually do not practical experience any conflict between faith and science. On the contrary, my faith stimulates me to perform science, for being open-minded on the earth.’

2007, 1st real-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence duration of ends of microtubules; and settled the system of biosensing with carbon nanotubes

2010, created a brand new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by means of graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into strong-state nanopores

Our research ranges with the biophysics of DNA to synthetic cells and beyond. You should have a look down below with the spectrum of our present jobs.

You are a Christian. If you could make this kind of artificial cell, would you be 1 step nearer to God, or would the position of God have diminished considerably once more?

2000, discovery that nanotubes can have remarkable substantial latest densities; solved the controversial concern of electronic transportation by means of DNA molecules by measurements of insulating habits at The one molecule degree; and demonstration of an AFM procedure for one-molecule manipulation of nanotubes

What if, as opposed to employing regular top rated-down silicon electronics, transistors can be built from The underside up using one organic molecules as the switching elements? This concept, which turned The premise of now’s industry of molecular electronics, to start with emerged during the nineteen seventies.

Dekker started off his research on single carbon nanotubes in 1993 when he put in place a different line of research to study electrical transport by way of one organic and natural molecules involving nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was achieved inside a collaboration Together with the team of Nobel laureate Richard Smalley. STM and nanolithography procedures were being used to demonstrate that these nanotubes are quantum wires at the single-molecule level, with exceptional Bodily Homes.

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Later on we spoke yet again briefly mainly because Dekker felt that our discussion of ceesdekker his religion swiftly turned purely philosophical, While it also concretely will help him in his function.

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes

Solid-condition nanopores have verified to get a incredibly adaptable probe for solitary-molecule Evaluation of DNA. I'll explain a number of our modern results – precisely DNA knots – and our attempts to develop the capabilities of sound-state nanopores even even further, from the direction of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.